| Achievement | How to unlock
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|---|
| - Kill 2 enemies with one javelin
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| - Escape the asylum with help from the inside
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| - Finish all chapters in New Game+ on any difficulty
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| - Rescue Jackie from the Iron Maiden
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| - Kill Jean-Luc Lambert and Amelie Dubois
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| |
| - Earn a score of over 1000 in each of the carnival games
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| |
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| - Kill 50 enemies with the Demon Arm Slash attack
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| - Kill 100 enemies while dual wielding 2 different guns while playing as Jackie
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| - Complete a mission as Inugami
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| |
| - Refuse to cooperate with Victor in the Interrogation
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| - Finish the game on Don difficulty
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| - In Vendettas, acquire all the talents for one character
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| - Survive the interrogation
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| - Kill 50 enemies with Executions while playing as Jackie
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| - Finish the game on any difficulty
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| - Complete a mission as Shoshanna
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| - Find and interrogate Swifty
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| - Kill 15 enemies while playing as the Darkling
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| - Complete a mission as Jimmy
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| - Purchase a Talent in the single player campaign
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| - Kill a shielded enemy with his own shield
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| - Pick up 5 Relics in the single player campaign
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| |
| - Kill 25 enemies while being dragged from the restaurant, without dying or restarting checkpoint
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- Ready for the Big Leagues
| - Kill 50 enemies with thrown objects
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| - Find all 29 Relics in the single player campaign
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| - Real guys know how to dance
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- Should Have Called 555-2368...
| - Survive the battle against the Hell Beast
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| - Throw an enemy into the air and kill him with gunfire before he lands
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| - Kill 50 enemies with Black Hole while playing as Jackie
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| |
| - Max out all of Jackie's Talent Trees
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| - Kill the NewsWatch 6 team of Tom Dawson, Bud Langley and Sara Stephens
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| - Impress Dolfo in two different ways
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| - Avoid being run over in the parking garage
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| - Complete Vendettas Campaign
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| - Kill 100 enemies with Gun Channeling while playing as Jackie
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| - Kill 50 enemies who are swarmed while playing as Jackie
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| - Max out 1 of Jackie's Talent Trees
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| - Max out 3 of Jackie's Talent Trees
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| - Kill enemies in 5 different ways within 30 seconds
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- Voodoo is More Than Dolls
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| - Complete 6 Hit List exclusive missions
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