These difficulty modes feature stronger enemies and new enemy formations.

Unlockable	How to unlock
Heaven or Hell	Complete Vergil's Downfall on Son of Sparda difficulty.
Hell and Hell	Complete Vergil's Downfall on Heaven or Hell difficulty.
Son of Sparda	Complete Vergil's Downfall on Human, Devil Hunter, or Nephilim difficulty.
Vergil Must Die!	Complete Vergil's Downfall on Son of Sparda difficulty.