Go to a billboard on a roof and kick it to change it to a funnier version. For example, in Las Vegas by the large slot machine there is a "Beauty's Only Skin Deep" billboard. Kick the woman in the face to see the girl from The Exorcist.

Item effects

Bananas: Good for George
Chili Peppers: Good for Nick
Fire: Good for Nick
Poison: Good for Kingston
Steak: Hurts Rojo
Water: Venus can drink water from pipe leaks. Gilman is immune to water leaks.