| Trophy | How to unlock | Type
|
|---|
| - Defeat Doctor Doom in Chapter 8.
| |
| - Complete 24 different Special Events in Story Mode.
| |
| | |
| - Defeat Doctor Octopus in Chapter 1
| |
| - Defeat 150 Super Villains in Midtown Manhattan.
| |
| - Find and Defeat a Cosmic Doop.
| |
| | |
| | |
| - Open 50 Bounty Chests in Operations.
| |
|
| - Defeat 7 Different Super Villains in their Showdowns.
| |
| - Complete the Super Heroic Trial with any hero.
| |
| - Complete 50 Legendary Quests.
| |
| - Apply a Modification to an Artifact.
| |
| - Defeat Elektra in Chapter 3.
| |
| - Visit Six Different Headquarters.
| |
| - Fully upgrade a Legendary Item.
| |
| - Level any vendor to level 10.
| |
| - Rescue 100 civilians in Midtown Patrol.
| |
| - Defeat Juggernaut in Chapter 5.
| |
| - Defeat The Hood in Chapter 2.
| |
| - Collect any 100 Relics of the same type.
| |
| - Defeat Mister Sinister in Chapter 7.
| |
| - Complete 14 Different Operations.
| |
| - Complete the Cosmic Trial with any hero.
| |
| - Defeat Magneto in Chapter 6.
| |
| - Reach level 60 with any hero.
| |
| - Get Five Heroes to Level 60.
| |
| - Defeat a Training Room Target Dummy.
| |
| - Collected all other Marvel Heroes Omega trophies.
| |
| | |
| | |
| - Complete Chapter 9 in Story Mode.
| |
| - Defeat The Kingpin in Chapter 4.
| |
| - Explore all of the Treasure Rooms in each chapter of Story Missions.
| |
| - Defeat Green Goblin in the Prologue.
| |
