Easy "Life's Manager" achievement
Prepare by accumulating at least 10 tresvigintillion bucks. Reset, then purchase the first twenty two Managers all at once. The last person you should be able to afford is the "Louis Fittui" Quick-Buy Upgrades manager. Purchase the maximum Lemonade Stands that you can afford, followed by all the Cash Upgrades that are affordable. Begin acquiring Angel Upgrades individually, avoiding ones that add +10/30/50 to any other businesses. Note: do not use the "Buy all SAFE Upgrades" button or you will get upgrades for unwanted businesses and disqualify you from earning "Life's Manager" Because you cannot scroll past the next 27 available Angel upgrades, at some point you will be unable to purchase all the Angel upgrades that you can currently afford. After your list is filled with only upgrades that give free businesses, stop purchasing Angel upgrades. The last useful Angel Upgrade you will be able to acquire should be "Hark! (Angel Investor Effectiveness +10%)". You will have to purchase a few more x3 upgrades (only one more for lemon), then you will reach another +30 News upgrade and have to stop buying Angel upgrades. You will now have maxed out your allowed Angel upgrades and must begin alternating between buying all available cash upgrades, and purchasing maximum lemonade stands. You have to occasionally purchase any of the final ten managers that you can afford. The last manager will be "Chill" at 9 unquadragintillion bucks.