If you have multiple targets, try to use an angle that groups them together. This will require a weapon with a faster reload time, to less the time spent relocating your targets. When you are hunting multiple aggressive targets (for example, wolves or bears), target the nearest one first. Once your presence is known, they will charge you. You will have more time to bring them all down the further they have to travel to get to you. However, you can allow them to get close-up if you need a particular shot to an organ.