As an all-around trivia game show, Jeopardy has a variety of categories, covering sports, current events, entertainment, history, science, the whole works. But unless you're a super trivia buff with knowledge across different specializations, you'll likely see a few topics or more that you aren't quite familiar with. Choose the ones you know the best, especially if you're up against the AI, as you'll be allowed to make the first choice. When it comes to PvP, you may choose to start first or have your opponent choose the category - if an opponent chooses the category and you're not well-versed with it, however, you may be a disadvantage. Either way, don't gamble on anything you aren't too familiar with.