Layout
Construct similar buildings close together to save time. For example, place the garden near the kitchen, and have that near the quarters. Build your weapons rooms close to a monolith so that minions will not travel far to reach them. Place one weapons room each per quarter. If you do not have enough weapon rooms, you will have minions that are unable to offer defense. Keep your base compact. It will be easier to defend and manage.
Monoliths
Quickly build your way to a monolith, then concentrate on a another one. You must keep up the pace due to the increasing speed of enemies with each wave. Each monolith gives you a special boost. Start with the speed monolith to speed up your minions. Then, build the monolith that slows down your enemies. Follow that with the monolith that offers a boost to attack range. Finally, choose the extractor bonus monolith.
Trade Soldiers
Focus on how you have actually rostered the tasks of your minions. Swiping left and right in between classifications will send out minions backward and forward in between tasks. Simply know where minions are at any one time, so that you effectively trade soldiers in between various resource requirements.