CPU pitchers with low Control ratings will throw a lot of balls. Be patient and wait for the right pitch. Tap the screen just as the ball is crossing the plate for a perfectly timed hit. This requires practice, especially with curveballs. They will veers far to one side then turn and glide over the plate as it gets closer. Once you learn how they appear, you can adjust your timing to get good swings on them. Increase your audio volume. You can hear the sound of the ball hitting the ground when it is low. Hold your swing if you hear it. Consider bunting with players that have a six or higher in that skill. A sacrifice bunt will always work when executed correctly. Note: You cannot use the bunt option if the count includes two strikes.
Do not swing if the count is 3-0, and the pitcher appears to be tiring. An easy walk still gets you on base. Use the "Batting Order" option under "Gameplan" and consider setting it to "VsLeftAndVsRight". This will make it easier to judge pitches coming in from the opposite side. Because you cannot set the batting order manually, this will allow you to have some good hitters that will bat from the better side of the plate. Use pitch-hitters in tight situations when you have a weaker batter at the plate.