At the beginning of the battle, shoot at either Evil Marie's body or head until her clothes have fallen off or her face has been bloodied. Thereafter, focus on her weak point the hickey on her neck. Marie is a formidable foe who is best attacked with a friend.
Defeat "Eyeclops" Easily
To defeat Eyeclops, you will need to shoot every eye on his body. Although this sounds difficult, it really isn't. Rapid fire (and a decent aim) is the key. Shoot the eyes on his chest first, then go for the extremities!
Defeat "Hambone the Revenge" Easily
Like his precursor, Hambone the Revenges' weak point is his Gattling gun. (For this battle though, you should definitely have the machine gun.) Unload on his gun, which shoots skulls instead of bullets. If you are playing alone, only three skulls should be fired; but with two players Harbone may fire six. Hambone the Revenge is probably the only end-boss that is best tackled alone.
Defeat "Hambone" Easily
The main weak point of Hambone, level one end-boss, is his large Gattling gun. That's right, just keep shooting as fast as you can at his gun and you will waste his energy and keep him from shooting at you. During the brief moments when he is not shooting, fire at either his head or legs but be sure to keep shooting the gun. As the screen moves from the right side of the hallway to the left, grab the shotgun that appears! Marksman lose very little energy on Hambone.
Defeat "Junior" Easily
Junior, the last end-boss, is the easiest to defeat. It's quite possible to beat him without getting a scratch. You will need to shoot every part of Junior's pudgy body until it turns red which means targeting the head, limbs and even his diaper! During one of his tantrums, when he rips apart the roof and vomits, make sure that you shoot the last morsel of yellow upchuck. (If you don't, Junior's last meal is on you!) When he's all red, shoot the darker leg and give him his final spanking!
Defeat "Krampus" Easily
Karmpus, the fourth level end-boss, is probably the toughest enemy that you will have to face. Shoot at his head and chest until these areas are bloodied. Then concentrate on his chest, which will open and expose the heart his main weak point. Krampus' legs and groin are also vulnerable. And in two-player games, it's best for each character to train his firearm either above or below the torso.
Easy Kills
When starting the game don't go to the hauted house, either go to the freak show or the other one. After you beat the the other stages go back to the hauted house and keep on shooting the mini-boss in the facemask until his mask comes off - then shoot him in the arms until you see one blow off. The next time you battle with him shoot him in the head and the missing arm that will give you a chance to survive him. After that you will encounter the main boss. Start to shoot her clothes off, that will make her weak so that you can beat her easily {you can do this on any boss or mini-boss}.
End-Boss Weakness
To defeat an end-boss easily, concentrate on his/her weak point.
Level Boss Weakness
1 Hambone Gattling gun
2 Hambone the Revenge Gattling gun
3 Evil Marie Hickey on her neck
4 Krampus Heart
5 Eyeclops Eyes
6 Junior Everywhere!
Party Hats and Afros
At the stage-select screen, choose the Haunted House stage, then pump the shotgun five times before the stage starts. You'll see that the zombies and other characters will have crazy hats and even afros on their heads.