1. Stay in king's tower as long as possible and get as much money as possible
2. Don't buy a house until you have at least between 5,000-20,000 simeolins.
3. Make friends with everyone you meet at least 75 relationship points.
4. When you go into the bayou and meet Crawdad Clem, he calls you a vampire be prepared you don't get too smartalliky other-wise you won't be able to talk to him for a while, or at least until you talk to the croc-dude, and then the red fiddler.
5. Get all the Xizzle beads you can(they'll come in handy).
6. Work on all the mini-games in the gameplay, play until you have around 30,000-50,000 because you'll have much better things to spend it on.