1st bottle: In southern swamp, go to Koume and then tell Kotake what happened to her. She will give you a potion to take to her and she will let you keep the bottle.

2nd bottle: When you defeat goht and spring arrives in the mountains, go to the goron racetrack. Finish in first place and the goron baby will give you a bottle filled with gold dust.

3rd bottle: In romani ranch, defeat the aliens until morning and protect the ranch. The girl will give you a bottle filled with milk.

4th bottle: In great bay, hook on to the pillars that lead to the beavers' home. Follow the first beaver in the loops, then the harder one. When you beat them, they with give you an empty bottle.