There are two bonus items per scenario. Get an "A" or better rank under the Normal difficulty setting to unlock the first item. Get an "S" rank on the hard difficulty setting to unlock the second item (and first item if not already unlocked).
Battery: Dark Legacy 2 with an "S" rank
Blue/Green Leech Charm: Train Derailment 3 with an "A" rank
Blue/Red/Green Chemical: Umbrella's End 2 with an "A" rank
Blue/Red/Yellow Gemstone: Rebirth 2 with an "A" rank
Book of Wisdom/Future Compass: Raccoon's Destruction 1 with an "S" rank
Briefcase: Train Derailment 1 with an "S" rank
Chronos Key: Raccoon's Destruction 3 with an "S" rank
Clark/Gail X-Ray: Rebirth 1 with an "A" rank
Crystal/Obsidian/Amber Ball: Raccoon's Destruction 3 with an "A" rank
Cylinder Shaft: Nightmare 1 with an "A" rank
Death Mask: Rebirth 2 with an "S" rank
Eagle/Serpent/Jaguar Stone: Fourth Survivor with an "S" rank
Emblem/Gold Emblem: Nightmare 2 with an "S" rank
Film A/B/C/D: Umbrella's End 1 with an "S" rank
Fire/Water Key: Beginning 2 with an "A" rank
Fuel Canteen: Mansion Incident 3 with an "S" rank
Great Eagle/Wolf Medal: Mansion Incident 1 on the Hard difficulty with an "S" rank
G-Virus: Fourth Survivor with an "A" rank
Hex Crank: Nightmare 1 with an "S" rank
Ink Ribbon: Umbrella's End 3 with an "S" rank
Joint N/S Plug: Raccoon's Destruction 2 with an "A" rank
King/Knight/Bishop/Rook Plug: Dark Legacy 1 with an "A" rank
Last Book, Vol. 1/2: Nightmare 2 with an "A" rank
Lighter/Lockpick: Mansion Incident 1 on the Normal difficulty with an "A" rank
Lighter Fluid: Raccoon's Destruction 2 with an "S" rank
Medium Base: Dark Legacy 1 with an "S" rank
Microfilm A/B: Beginning 2 with an "S" rank
Mixing Set: Train Derailment 1 with an "A" rank
MO Disk: Mansion Incident 3 with an "A" rank
Motherboard: Beginning 1 with an "A" rank
Picture (Ada and John): Death's Door with an "A" rank
Plastic Bomb/Detonator: Umbrella's End 1 with an "A" rank
Relief of Discipline/Obedience/Unity: Train Derailment 2 with an "S" rank
S.T.A.R.S. Card (Brad): Death's Door with an "S" rank
S.T.A.R.S. Card (Jill): Raccoon's Destruction 1 with an "A" rank
Slide Cartridge: Rebirth 1 with an "S" rank
Spade/Diamond/Club/Heart Key: Dark Legacy 2 with an "A" rank
Square Crank: Umbrella's End 2 with an "S" rank
Statue of Good/Evil: Train Derailment 2 with an "A" rank
Sterilizing Agent: Train Derailment 3 with an "S" rank
Sun/Star/Moon Crest: Mansion Incident 2 with an "A" rank
V-Jolt: Mansion Incident 2 with an "S" rank
Vaccine: Umbrella's End 3 with an "A" rank
Valve Handle: Beginning 1 with an "S" rank
Bonus scenarios
Complete the indicated task to unlock the corresponding bonus scenario.
Beginnings 1: Complete Train Derailment 3.
Beginnings 2: Complete Beginnings 1.
Dark Legacy 1: Complete Fall Of Umbrella 3.
Dark Legacy 2: Complete Death's Door.
Death's Door: Complete Racoon's Destruction 3 with an "A" or better rank.
Fourth Survivor: Complete Dark Legacy 2.
Nightmare 1: Complete Mansion Incident 1.
Nightmare 2: Complete Nightmare 1 with an "A" or better rank.
Rebirth 1: Complete Mansion Incident 3.
Rebirth 2: Complete Rebirth 1.
The 4th Survivor: Complete Dark Legacy 2.
Control loading screen
During the loading screen, you can shoot the Umbrella logo where it will eventually fall. It will bounce around as you shoot it.
Cooperative mode
Complete "The Fourth Survivor" sub-mission to unlock Cooperative mode in any mission. You can now select the double pistol icon at the character selection screen to play with two players. Note: Both players will use the same character.
Defeating Cerberuses
Shoot at the head or wait until you see their faces open in your face before they bite you. You can kill them with one shot almost every time.
Defeating Chimeras
When they are on the floor, shoot them in the head to kill them. When they are crawling on the roof, shoot them with the shotgun or an automatic because it will be difficult to kill them while they are there.
Defeating Hunters
To kill the Hunters in one shot with any weapon, shoot them while they are jumping in the air or at you.
Defeating Ivys
Wait until they open their mouths and shoot. Sometimes they can be killed with one shot.
Defeating Lickers
Shoot at their heads with any weapon. Three or four criticals will kill them.
Defeating Nemesis
In order to defeat him, throw everything you have at him. He has no weak point. Make sure you have a Magnum (level 4), assault shotgun (level 4), and MRL (level 4). Use the Magnum first. After you shoot him enough times, he will jump onto the rooftop and run around to a certain spot, where he will shoot his tentacles down the wall and pop up directly in front of you to attack. This cannot be dodged. He will then jump up and attempt to crush you. Dodge this, and repeat the process. When you run out of ammo for the Magnum and assault shotgun, use the MRL. Shoot all eight rockets at him. If he survives, finish him off with the handgun. Note: He can grab you and hold you in the air. This will damage you until you die or shoot him enough times to make him let you go.
Defeating the Giant Worm
He will be moving left and right at the beginning, however this is just to confuse you on which side he will be attacking from. His weak point is in his mouth. You should be using the assault shotgun, Magnum, rocket launcher, or MRL. He will go underground a few times to attack you. Dodge this attack. When he comes back up, Carlos or Jill will look up into the sky. Shoot the rocks coming down and repeat the process. He will jump into the air a few times. Shoot his mouth to send him flying to the side. You must dodge one of these attacks later. Once his health gets down to half, shoot all four MRL rockets into is mouth. If he lives, finish him off with the assault shotgun. Note: In one of his attacks, he will throw cars at you. One of them will be a bus, which will take out half of your health. Shoot them to make them explode.
Easy "S" ranks
Use the following trick to get easy "S" rank unlocks. Play Wesker's Mansion Mission (Rebirth). Play the first scenario repeatedly. Once you find all three files, all you need to worry about is time and critical hits. It is also a short mission. Playing it over and over again will not be a chore. Once you get the three files, getting an "S" rank all the time will be easy. The best time to get all your critical hits is after going up the steps. Once the zombies begin moving, aim your crosshair until the red circle blinks, then fire for an instant critical.
Handcannon
Play Hunk's Fourth Survivor scenario. Locate the secret room next to the front doors of the police station lobby. Watch for Hunk to look briefly towards the doors that lead to the secret room as he walks past. Quickly shoot the doors to open them. Enter the secret room and get the Handcannon from the desk on the left side.
Special Stage mini-game
Successfully complete all scenarios, including the bonus sub-scenarios.
Unlimited ammunition
Earn an "S" rank on all scenarios. The message "Unlimited Ammo Deactivated" will appear. This is a glitch, where "Deactivated" was used as a mistranslation for "Unlocked". Ignore the error, and enter the "Customize" menu to purchase the level 5 (unlimited ammo) upgrade.
Unlock Bonus Characters in Mercenaries Mode
When you play Mercenary mode and get a 4 Star or higher rank in a map the following characters can be unlocked.
Unlock Ada Wong the Secret Agent:
Get a 4 Star rank in the Pueblo map.
Unlock Jack Krauser the Army Veteran:
Get a 4 Star rank in the Castle map.
Unlock Albert Wesker the Leader of Alpha Team:
Get a 4 Star rank in the Waterworld map.
Unlock Hunk the Operative for the Umbrella Corporation:
Get a 4 Star rank in the Island map.
Weapon Glitch
This is a great way of getting weapons, all you have to do is go to the inventory screen and select the 'Stricker'. When you exit the inventory press the B button followed immediately after by the minus button and you will now be able to equip any weapon you want (except the Striker) and move and shoot twice as fast as normal. To deactivate this glitch just select the Stricker.
