When you are being chased by enemies in a car, let them drive up on your side. Usually they will come up near your rear on your left or right. Then, look ahead and lure them into an accident. Usually they will smash into something like oncoming traffic or a wall if timed correctly. They will eventually come back and catch up to you, but if you keep doing this they will eventually blow themselves up (because you cannot shoot out your car at them).