Masako has some nasty weapons and a shield. The only weapon that can defeat her is the powerful assault rifle. She first attacks with a ship firing rockets and machine guns. Equip the laser to blow it up in one shot. Then Masako herself appears with a shield, just like Capek. However, she uses a precision rifle very fast. Keep moving and destroy her shield with your rifle. Then, keep your rifle armed to kill her. Take her Precision Rounds after she has been defeated.