To unlock all 6 endings in Saira, you will need to acquire all items from each planet in the game. Return to the first planet (Lemond) and use the items in the teleporter with the following combinations: (Please note: other combinations are possible to produce the same endings).

Unlockable	How to unlock
Knytt Ending (Cameo Ending)	Targeting: basic + Impulse: high power + Fuse: high power
Lemond Ending (Bad Ending)	Targeting: basic + Impulse: homebrew + Fuse: standard
Skomvaer Ending (Bad Ending)	Targeting: basic + Impulse: regular + Fuse: standard
Total Failure (Bad Ending)	Targeting: basic + Impulse: regular + Fuse: high power
True Ending	Targeting: extra precision + Impulse: high power + Fuse: high power
Universum Ending (Neutral Ending)	Targeting: extra precision + Impulse: regular + Fuse: standard