The Nuke can be found in three multiplayer levels: Tears Of Horatio, Withering Heights, and Dino-Depot. Note: Do not have the "Unlimited Ammo" option in the multi-player options menu activated or the Nuke will not appear. You can still use the "Unlimited Ammo" cheat in the cheat menu and get the Nuke. The "Unlimited Ammo" cheat does not give you unlimited Nukes. The Nuke will respawn after a period of time.

Tears of Horatio: Go up either path, up the cliff, until you reach a big metal platform with three holes in it. Turn around and you will face a huge rock pillar. A Swarm Bore canister will be at the foot of the pillar. Directly above the Swarm Bore canister is the Nuke, floating in the air. You must have the Jump Boots to get it.

Tears Of Horiatio: Get the nuke and stay up there. If your friend approaches, shoot the nuke directly at the ground below you and do not move. It will not touch you, but will kill anyone around you. There is also a good hiding spot in at the end of that level, where there are cannons. Go on one of the side cannons and go to the very end. Then, turn around and quickly hit back and then forward. You should get stuck. Try jumping a lot until you are in it. If you do not go in, drop a little bit farther and try again. This place is a good hiding spot from trackers like the plasma cannon.

Withering Heights: Go to either side of the level and climb to the top floor. Activate the switch, then go to the window where there is a trampoline at the bottom (after switch is activated). Jump down to it and you will bounce to the center platform. Once there, you will get a either the Empathy Chest Plate or a Nuke (along with a Swarm Bore canister).

Withering Heights: Do not flip the switch as described above. If you do this and jump to the center platform, you will be killed by a trap cage. Instead, just jump out the window above the disagreeing trampoline and it will appear for you.

Withering Heights: It is small but easy to get around because of the trampolines. The nuke is in the center. You can get it and aim it directly down at where you stand for and instant kill for all around.

Dino Depot: The Nuke can be found on the top of the yellow box car. You must have the Jump Boots to reach it.