| Achievement | How to unlock
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| - Collect all of the mysterious artifacts.
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| - Complete the game using only the dual pistols.
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| - Find a shield or weapon upgrade.
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| - Find the assault rifle blueprint.
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| - Find the grenade launcher blueprint.
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| - Find the rocket launcher blueprint.
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| - Find the shotgun blueprint.
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| - Find the sniper rifle blueprint.
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| - Complete the game on hardcore difficulty.
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| - Blindly jump off the edge in the Gate Fortress.
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| - Complete the game on normal difficulty.
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| - Kill the Hell Spider boss using the chandelier.
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| - Find all of the weapon blueprints.
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| - Complete the game on any difficulty in New Game+ mode.
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| - Defeat The Corrupted without taking any damage.
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| - Defeat The Demon without taking any damage.
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| - Defeat The Djinn without taking any damage.
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| - Defeat The Frozen without taking any damage.
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| - Defeat the Hell Spider without taking any damage.
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| - Defeat The Shadow without taking any damage.
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| - Defeat The Shapeshifter without taking any damage.
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| - Complete the game on easy difficulty.
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| - Find all of the shield upgrades.
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| - Defeat Mephistopheles without taking any damage.
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| - Complete the game without upgrading any of the weapons.
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| - Complete the game on hard difficulty.
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