Detroit: Double Secret power-ups
Use the nuke to clear out a section in the west. To do this, turn around after finding the nuke, head west, drop the nuke, and get out of there. When detonated, this will reveal a "Double Secret" pick-up. Pick it up to get super speed, then head south. You will see a Gun Buddies power-up. Use this to your advantage. Directly behind this power-up is a secret room. Enter the room to collect another "Double Secret" power-up.