Napalm bombs
Most levels and Bosses can be defeated in under three minute with the Napalm Bombs. While the range of these bombs is limited, the amount of damage they do is larger that any other weapon in the game. Get very close to the enemy and always stay to the right or left of the place where the Bosses are shooting. Remember when Napalm Bombs explode, many things around them are damaged, not just where you see the explosion. Note: Be more concerned about dodging shots than shooting the enemy -- as soon as your health is gone, it is gone.