Successfully complete the game under any difficulty setting to unlock the following bonuses:

"History Of Resident Evil" option
"Infinity ammunition" option (must fully upgrade a weapon then purchase the unlimited ammo from the "Bonus Features" section with points)
Chris' Safari and Sheva's Clubbin' alternate costumes
Mercenaries mode
New Game+ mode
Play as Sheva Alomar

Successfully complete the game under five hours (get an "S" rank) under any difficulty setting to unlock the Infinity Rocket Launcher.

Successfully complete the game under the Amateur difficulty setting to unlock the "Classic Horror Filter" option.

Successfully complete the game under the Normal difficulty setting to unlock the "Retro Filter" option.

Successfully complete the game under the Veteran difficulty setting to unlock the following bonuses:

"Noise Filter" option
Professional difficulty