Beat either Leon's, Chris's or Jake's campaign once.
Alternate ending
Complete Ada Wong's campaign to view a video after the credits.
Alternate sniper rifles uses
The sniper rifle is useful for inflicting damage on distant enemies, but incorporating the quick-shot action will double its use as a close-quarter weapon. This will substitute any shotgun, the Desert Eagle, and the Elephant Killer when ammo is scarce for them. Piers' anti-material rifle is a one hit-kill on most enemies near or far.
Curious Fan Title
Complete the Resident Evil 5 Campaign to unlock the "Curious Fan" title.
Easy "B.O.W.s Are Ugly" trophy
Play the final chapter of Chris' storyline and progress to checkpoint 5-1. Continue until you enter a circular room surrounded by levers. You will be ambushed, and each lever will spawn two Chrysalid B.O.W.s, which you can pull yourself. After killing all ten of them, reload from the last checkpoint and repeat the process as many times as needed. Do not enter the next area or you will get a new checkpoint and have to repeat the entire first section of the level. Your kill progress will be saved even if you do not reach a new checkpoint.
Easy "Hard Choice" trophy
In Jake's campaign, when fighting the helicopter in Chapter 4 at the part where you see Chris, get on the top of the roof. You will find some ladders and boxes to destroy. The helicopter will sometimes drop enemies on ropes. Get near one of those ropes and press [Action]. Then, climb up and shoot the pilot to get the "Hard Choice" trophy.
Easy "I Prefer Them Alive" trophy
In Chapter 2 of Leon's campaign, after entering the cathedral, you must solve some puzzles to open the main chamber door in the center of the altar. Afterwards, you will encounter the Lepotitsa. It infects many humans in a short time by releasing C-Virus gas. You must save at least two females in the cathedral. To do this, shoot it as quickly as possible while remaining at a safe distance. However, do not position yourself too far away or you will lose sight of it and it will infect too many people. If you do enough damage, it will expose its weak areas and get on its knees. Once this happens, get close and perform a melee attack for increased damage. Note: This will require a large amount of ammunition on the higher difficulties. Consider doing this after completing the campaign, in order to have better weapons and perhaps infinite ammunition.
Extra Content stages
Complete the indicated task to unlock the corresponding stage. Note: Levels must be unlocked separately for each Extra Content type (Mercenaries, Siege, Predator, etc.)
Stage 4: Rail Yard: Complete Mining the Depths with a "B" rank.
Stage 5: High Seas Fortress: Complete Rail Yard with a "B" rank.
Stage 6: Catacombs: Complete High Seas Fortress with a "B" rank.
Stage 7: Requiem for War: Complete Catacombs with a "B" rank.
Stage 8: Liquid Fire: Complete Requiem for War with a "B" rank.
Stage 9: Rooftop Mission: Complete Liquid Fire with a "B" rank.
Stage 10: Creature Workshop: Complete Rooftop Mission with a "B" rank.
Hidden video
After you have defeated every 4 campaigns a video clip will become unlocked which will start right after every credit video from any of the campaigns.
Infinite Ammo skill
Complete all four campaigns to unlock the Unlimited Ammo skill for each weapon.
Interacting with the playground
Near the beginning of Chapter 3 in Chris' campaign, there will be a children's playground on your left, after passing through the alleys. Both Chris and Piers can interact with the panda ride, jungle gym, and two slides at the playground.
Mercenaries mode Bosses
Complete the indicated task in the listed level to unlock the corresponding hidden Boss.
Boss
How to unlock
Gnezdo (Steel Beast)
Get 25 Coup de grace attacks before 80 kills.
Gnezdo (High Sea Fortress)
Get 40 melee kills before 80 kills.
Napad (Urban Chaos)
Get 15 Counter Kills before 80 kills.
Strelat (Mining the Depths)
Kill 70 enemies before 600 seconds.
Strelat (Catacombs)
Get 20 Quick Shot Kills.
Ubistvo (Rail Yard)
Get 25 Quick shot kills before 80 kills.
Mercenaries mode characters
Complete the indicated task to unlock the corresponding character in Mercenaries mode.
Character
How to unlock
Ada
Complete Ada's Campaign.
Carla
Unlock all other characters' costumes.
Helena
Complete the Urban Chaos map with a "B" or higher rank.
Piers
Complete the Steel Beast map with a "B" or higher rank.
Secret BSAA Soldier
Unlock all other characters and their costumes.
Sherry
Complete the Mining The Depths map with a "B" or higher rank.
Mercenaries mode costumes
Earn an "A" rank in Mercenaries mode with the indicated character to unlock the corresponding costume.
Costume
How to unlock
Pirate Leon
Earn an "A" rank as Leon.
Puffy Jacket Jake
Earn an "A" rank as Jake.
R.P.D. Helena
Earn an "A" rank as Helena.
Racer Piers
Earn an "A" rank as Piers.
Samurai Chris
Earn an "A" rank as Chris.
School Girl Sherry
Earn an "A" rank as Sherry.
White Dress Ada
Earn an "A" rank as Ada.
Mercenaries mode maps
Complete the indicated task to unlock the corresponding map in Mercenaries mode.
Map
How to unlock
Mining The Depths
Complete Jake's campaign.
Steel Beast
Complete Chris' campaign.
Quicker reloading
You can make a weapon's reloading animation shorter by quickly selecting an item (grenade, remote mine, first aid spray), and then switching back to your weapon. Alternately, press [Fire] (without aiming) to perform a gun-butt with the weapon and complete the magazine reload; however, this make your character do the gun-butt animation. This, and other actions (taking cover, diving, etc.), may be faster or slower than weapon switching, but will depend on the situation you are in. These methods allow you to cut down the animation delay periods for certain weapons (notably the grenade launcher), letting you shoot the weapon a few moments earlier. However, these tricks do not apply to weapons with manual actions, such as the six-shot sniper rifle, regular shotgun, Piers' Anti-Material Rifle.
Secret Trophies
Complete the following tasks to unlock PlayStation 3 trophy rewards.
Trophy
How to unlock
Ada's Demise (Bronze)
Complete Chapter 4 in Ada's campaign.
Counterintelligence (Bronze)
Complete Chapter 2 in Ada's campaign.
Flying Ace (Bronze)
Pilot the VTOL without getting a scratch on it.
Hard Choice (Bronze)
Shoot the helicopter pilot with a Magnum at point-blank range.
I Prefer Them Alive (Bronze)
Rescue two female survivors at the cathedral.
I Spy (Bronze)
Complete Chapter 1 in Ada's campaign.
RESIDENT EVIL 6 Platinum Trophy (Platinum)
Congratulations! You've overcome all your fears in RESIDENT EVIL 6!
Sneaking Around (Bronze)
Get through the aircraft carrier's bridge area without being noticed.
This Takes Me Back (Bronze)
Complete Chapter 3 in Ada's campaign.
What's Next? (Bronze)
Complete Chapter 5 in Ada's campaign.
Secret Video
After beating all 4 campaigns you will unlock a video that will play after any after credit video from any campaigns.
Titles
How to unlock the games Titles which are placed on your dog tag excluding weapon and enemy titles which are all unlocked at 300 kills for enemy expert title and 1,000 for weapon expert title.
Title
How to unlock
Action Junkie
Complete 200 campaign chapters.
Amateur
Complete all campaign chapters on Amateur (20).
Amazon
Complete 15 campaign chapters with female characters.
Any Port in a Storm
Use chrysalids for cover for 20 minutes.
Badass
Attack 100 times with zero stamina.
Big Baby
Crawl for 300 meters.
Bone Breaker
Kill 100 enemies while sliding.
By Any Means
Use an enemy's weapon 100 times.
Chuter Shooter
Kill 100 parachuting enemies.
Combat Master
Perform a unique physical attack 300 times.
Counter Attacker
Perform 300 counterattacks.
Curious Fan
Finished playing Resident Evil 5 campaign.
Dead Ringer
Be killed 200 times.
Death Wish
Require saving 100 times.
Decorated Agent
Earn all the different medals in the campaign (175).
Earning Them Medals
Earn 2,000 medals.
Easy Target
Require help 300 times.
Enjoying the Scenery
Walk 5,000 meters.
Executioner
Perform 300 coups de grâce.
Face Smasher
Destroy 1,000 J'avo masks.
Figure Collector
Collect all the figures (78).
File Collector
Read all the files (80).
Fire Hazard
Set 1,000 zombies on fire.
Getting Good Grades
Complete all chapters in the campaign with an S rank (20).
Global Player
Play with 300 other players online.
Going Out in Style
Be killed awesomely 50 times.
Got Some Experience
Complete all campaign chapters on Normal (20).
Gunslinger
Hit enemies with a quick shot 1,000 times.
Hardcore Player
Play Resident Evil 6 for 100 hours (Title changes).
Headshot Master
Make a headshot 1,000 times.
Herb Sharer
Feed your partner 200 health tablets during the campaign.
Hero
Rescue another player 300 times.
I Got Hand
Kill 100 enemies with Piers' mutated arm.
I Know What I'm Doing
Complete all campaign chapters on Veteran (20).
J'avo Juice
Play as a J'avo 300 times.
Joyrider
Travel 500 kilometers with a vehicle.
Kickin' Ass & Takin' Names
Defeat 10,000 enemies.
Last Hurrah
Defeat 100 enemies while dying.
Left My Mark
Tag 300 enemies with a marker.
Lifesaver
Save other players from dying 100 times.
Like a Duck to Water
Swim 1,000 meters.
Lone Wolf
Complete all campaign chapters by yourself (20).
Mad Dasher
Dash for 5,000 meters.
Manipulator
Use an enemy's attack to kill 300 other enemies.
Medal Agent
Earn 1,500 medals in the campaign.
Metal Muncher
Destroy 300 helicopters or tanks.
My Skills
Earn a total of 200,000 skill points.
Need a Pick-Me-Up
Consume 2,000 health tablets.
Need My Meds
Use the first aid spray 100 times.
Not an Acrobat
Use the zip-line 300 times.
Open Season
Kill 300 animals.
Party Time!
Play with 3 other players X times during a story intersection.
People Eater
Play as a zombie 300 times.
Phoenix
Recover on your own from dying 100 times.
Potent Pugilist
Land a physical attack 1,000 times.
Professional
Complete all campaign chapters on Professional (20).
Props to You
Praise your partner 100 times during the campaign.
Relentless Attacker
Perform 300 successful follow-up attacks.
Reloader
Reload 5,000 times.
Rescue Me
Receive help 300 times.
Resident Evil
Default title.
Respect the Skills
Complete all campaign chapters without seeing the game over screen (20).
Resuscitated Agent
Saved from dying 100 times.
Rock-Hard Buns
Traverse 500 meters on your backside.
Rollin' with the Homies
Play online with a friend X times.
Running My Shoes Off
Run 100,000 meters.
Skill Collector
Purchase 80 skills.
Slide 'n' Smash
Destroy 300 objects while sliding.
Slip Slider
Slide 500 times.
Stealth Killer
Perform 300 stealth kills.
Tag Master
300 enemies you tagged are killed by other players.
The Chemist
Combine herbs 1,000 times.
Title Collector
Earn 200 titles.
Undercover
Use cover for a total of 100 minutes.
Various Trophies
Complete the following tasks to unlock PlayStation 3 trophy rewards.
Trophy
How to unlock
A Revolting Development (Bronze)
Complete Chapter 2 in Jake's campaign.
After Her! (Bronze)
Complete Chapter 3 in Chris' campaign.
B.O.W.s Are Ugly (Silver)
Defeat 100 enemies that have come out of a chrysalid.
Back in My Day (Silver)
Complete the entire game on Veteran.
Big Trouble in China (Bronze)
Complete Chapter 4 in Leon's campaign.
Bob and Weave (Bronze)
Counter an enemy's attack three times in row.
Bring the Heat (Bronze)
Take down an enemy from 50 meters away with a headshot using the thermal scope.
Buried Secrets (Bronze)
Complete Chapter 2 in Leon's campaign.
Check Out My Dogs (Bronze)
Customize your dog tags.
Covered in Brass (Silver)
Earn 150 different medals.
Down, Not Out (Bronze)
Defeat an enemy while dying, then recover without any help.
Duty Calls (Bronze)
Complete Chapter 5 in Chris' campaign.
Finish What You Start (Bronze)
Perform a coup de grâce on ten enemies.
Get on the Plane (Bronze)
Complete Chapter 3 in Leon's campaign.
Give a Little Push (Bronze)
Knock ten enemies off a high place.
Gone to Hell (Bronze)
Complete Chapter 1 in Leon's campaign.
Green around the Ears (Bronze)
Complete the entire game on Amateur.
Heirlooms (Silver)
Collect all the serpent emblems.
High Voltage (Bronze)
Defeat ten enemies with a stun rod charge attack.
J'avo Genocide (Bronze)
Defeat 500 J'avo.
Leave It to the Pro (Gold)
Complete the entire game on Professional.
Let's Blow This Joint (Bronze)
Complete Chapter 3 in Jake's campaign.
Lifesaver (Bronze)
Help or rescue your partner ten times.
Mad Skillz (Gold)
Max out all the skills that allow you to level up.
Money Talks (Bronze)
Complete Chapter 1 in Jake's campaign.
Normal Is Good (Silver)
Complete the entire game on Normal.
One Is Better Than None (Bronze)
Purchase one skill.
Rescue the Hostages (Bronze)
Complete Chapter 1 in Chris' campaign.
Rising Up (Silver)
Earn a level-four title.
See You Around (Bronze)
Complete Chapter 5 in Jake's campaign.
Silent Killer (Bronze)
Use a stealth attack to take down five enemies.
Still on the Run (Bronze)
Complete Chapter 4 in Jake's campaign.
Stuntman (Bronze)
Defeat 20 enemies with the Hydra using a quick shot.
The Longest Night (Bronze)
Complete the tutorial.
The Trouble with Women (Bronze)
Complete Chapter 5 in Leon's campaign.
There's Always Hope (Bronze)
Complete Chapter 4 in Chris' campaign.
They're ACTION Figures! (Bronze)
Collect 3 figures.
Titular Achievement (Bronze)
Earn 10 different titles.
Tragedy in Europe (Bronze)
Complete Chapter 2 in Chris' campaign.
Weapons Master (Silver)
Use all the weapons in the game and kill ten enemies with each of them.
Zombie Massacre (Bronze)
Defeat 500 zombies.
Various Trophies
Complete the following tasks to unlock PlayStation 3 trophy rewards.
Trophy
How to unlock
Kung Fu Fighting(Silver)
Survive to the end only using physical attacks.
Last Man Standing Again(Gold)
Win five times in a row.
Staying Alive(Bronze)
Return to the game as a human character.
Take 'Em All Down(Silver)
Defeat 100 agents.
Team Effort(Bronze)
Win without any members of your team being killed.
Various Trophies: Onslaught DLC
Complete the following tasks to unlock PlayStation 3 trophy rewards.
Trophy
How to unloxk
Kill or Be Killed(Bronze)
Win while in the dying state.
Killer Combo(Silver)
Achieve a 30-combo chain.
Surrounded on All Sides(Gold)
Send 2,000 enemies to your opponent's map.
Take the Stage(Silver)
Defeat your opponent and achieve victory in 3 stages.
You Are S.O.L.(Bronze)
Defeat your opponent 10 times with enemies you sent.
Various Trophies: Predator DLC
Complete the following tasks to unlock PlayStation 3 trophy rewards.
Trophy
How to unlock
Easy Pickings(Silver)
Eliminate all players as Ustanak in less than a minute.
Held Captive(Bronze)
Defeat Ustanak with only one Agent remaining.
Invincible(Silver)
Defeat Ustanak without anyone on your team being captured.
Not without a Fight(Gold)
Defeat Ustanak 20 times.
One Is Never Enough(Bronze)
As Ustanak, capture a total of 50 humans.
Various Trophies: Siege DLC
Complete the following tasks to unlock PlayStation 3 trophy rewards.
Trophy
How to unlock
Civilian Casualties(Silver)
Defeat the BSAA 100 times.
Everybody Dies(Gold)
Defeat 100 player-controlled agents and 100 player-controlled creatures.
Murder Spree(Silver)
Defeat the BSAA as a creature without dying once.
Protect and Serve(Bronze)
Protect the BSAA without any of them getting hurt.
