In Chapter 24 when Flynn is forcing you to find a way to turn the bridge, turn and swing at him by pressing Square. He will dodge your attack, knock you down, and give you a message. If you try again, he will shoot and kill you
Chapter 6: Easy money
Locate the pool on a hotel roof. Jump in the pool and swim around to have Chloe and Nate start a game Marco Polo and get $10,000.
Crushing difficulty
Successfully complete the game under the Hard difficulty setting.
Defeating Guardians
To kill the Guardians you face late in the game easier, once you kill one take the gold crossbow it drops and use it on the others. It will kill them much quicker than your normal guns.
Defeating Lazarevic
To defeat Lazarevic, you must lure him near the volatile blue sap throughout the level. Shoot the sap causing it to explode when he is in range.
DLC Trophies - Drake's Fortune Map Pack
Complete each condition to get the allotted Trophies.
Trophy
How to unlock
Brass Knuckles ( Bronze )
Get 100 Melee Kills in Deathmatch or Elimination games.
Cold Blooded ( Silver )
Get 2500 Kills in Deathmatch or Elimination games.
Gold Digger ( Bronze )
Finish Wave 10 in 1 Gold Rush Game.
I Told You I Was Hardcore ( Bronze )
Complete All 3 Co-op Objective Maps on Hard Difficulty.
Made It ( Bronze )
Finish Wave 10 in 1 Survival Game.
Plays Well With Others ( Bronze )
Win 50 Objective Games.
Plundered! ( Bronze )
Get 200 Captured Medals.
Rapid Fire! ( Bronze )
Get 7 Tripled Medals in Deathmatch or Elimination games.
Sneaky... ( Bronze )
Get 50 Stealth Kills in Deathmatch of Elimination games.
Still Alive ( Bronze )
Win 50 Elimination Games.
Tastes Like Chicken ( Bronze )
Get 20 BBQ Medals in Deathmatch or Elimination games.
Wipe Them Out... ( Bronze )
Win 50 Deathmatch Games.
Expressions of Sully
When you are prompted to view your journal by pressing Select, if you keep flipping back you will find an entry with four pictures of Sully, which Nate has apparently drawn over and labeled according to his expression.
Multi-player mode boosters
Reach the indicated level to unlock the corresponding booster for purchase in Multi-player mode.
In addition to the multiplayer skins that you start with, there are more that you can eventually use. These skins that can be purchased in the multiplayer store after reaching certain levels.
Skin
How to unlock
Blain
Reach Level 80; Cost: Free.
Cameraman Jeff
Reach Level 30; Costs $100,000.
Doughnut Drake
Reach Level 60; Costs $2,000,000.
Dutch
Reach Level 70; Cost: Free.
Genghis Khan Villain Skin
Beat Crushing Difficulty. Cost: 1,500,000.
Harry Flynn
Reach Level 20; Costs $50,000.
Heist Drake
Reach Level 10; Costs $20,000.
Heist Flynn
Reach Level 20; Costs $50,000.
Karl Schafer
Reach Level 50; Costs $1,000,000.
Lieutenant Draza
Reach Level 50; Costs $1,000,000.
Marco Polo Hero Skin
Get the Platinum trophy. Cost: Free.
Skelzor
Reach Level 60; Costs $2,000,000.
Winter Chloe
Reach Level 20; Costs $50,000.
Winter Drake
Reach Level 40; Costs $250,000.
Winter Elena
Reach Level 30; Costs $100,000.
Winter Flynn
Reach Level 30; Costs $100,000.
Zoran Lazarevic
Reach Level 40; Costs $250,000.
Zorskel
Reach Level 10; Costs $20,000.
Prequel bonuses
Enter the store and press Square to detect a saved game file from Uncharted: Drake's Fortune. You will get $20,000 for having a saved game file, and an additional $80,000 for having a completed saved game file. The money can be spent in the single player and multi-player stores.
Run normally while injured
When Nate is injured, he can still run at normal speed while carrying a propane tank.
Siege Expansion Pack: Trophies
Complete the following tasks to unlock PlayStation 3 trophy rewards.
Trophy
How to unlock
Back At Ya (Bronze)
Get 50 Retaliation Medals.
Fallen Angel (Bronze)
Get 50 Afterlife Medals.
I'll Cover You (Bronze)
Get 50 Defender Medals.
Jack of All Trades (Bronze)
Get 15 Triple Threat Medals.
Kneel Before Z... (Bronze)
Get 5 Put-em Down Medals.
Not So Fast (Bronze)
Get 20 Shut'em Down Medals.
Rock a Rhyme (Silver)
Get 100 Tricky Medals.
Speedy (Bronze)
Get 10 First! Medals.
Under Siege (Bronze)
Finish Wave 10 in 1 Siege game.
You Can't Break Me (Bronze)
Complete all 3 co-op objective maps on Crushing.
You Run, I'll Shoot (Bronze)
Get 10 Protectorate Medals.
Skins
Complete the indicated task to unlock the corresponding skin to unlock it for purchase.
Chloe (Street Clothes): $5,000
Chloe (Winter Gear): $20,000, after Flynn clothes purchased
Dragan (Helmet Soldier): $5,000
Drake (Dirty and Beat-Up): $20,000, after Drake (Heist Gear) purchased
Drake (Doughnut Drake): $50,000
Drake (Heist Gear): $10,000
Drake (Street Clothes): Free
Drake (Winter Gear): $20,000 after Drake (Heist Gear) purchased
Elena (Street Clothes): $5,000
Elena (Winter Gear): $10,000, after Street Clothes purchased.
Flynn (Heist Gear): $10,000
Flynn (Street Clothes): $5,000
Flynn (Winter Jacket): $10,000
Jeff (Elena's Camerman): $5,000, after Elena (Winter Gear) purchased
Karl Schaefer: $20,000, after Tenzin purchased
Lieutenant Draza: $10,000, after Zorskel purchased
Lovac (Headphones Soldier): $5,000
Sark (Face Mask Soldier): $5,000, after Dragan purchased
Sir Francis Drake: $30,000, after Skelzor purchased
Skelzor the Skeleton: $30,000, after Dead Explorer purchased
Tenzin: $5,000, after Victor Sullivan purchased
Tetram (Gas Mask Soldier): $10,000, after Vodnik and Lovac purchased
The Dead Explorer: $20,000
Victor Sullivan: $5,000
Vodnik (Ski Mask Soldier): $5,000, after Sark purchased
Zoran Lazarevic (Healed): Free, after Lazarevic purchased
Zoran Lazarevic: $20,000, after Draza purchased
Zorskel (Skull Mask Soldier): $10,000
Trophies
Complete the following tasks to unlock PlayStation 3 trophy rewards.
Trophy
How to unlock
100 Headshots ( Bronze )
Defeat 100 enemies with headshots.
20 Headshots ( Bronze )
Defeat 20 enemies with headshots.
20 Kills: Pistole ( Bronze )
Defeat 20 enemies with the Pistole.
200 Kills: GAU - 19 ( Bronze )
Defeat 200 enemies with the GAU - 19.
250 Headshots ( Silver )
Defeat 250 enemies with headshots.
30 Kills: Desert - 5 ( Bronze )
Defeat 30 enemies with the Desert - 5.
30 Kills: Mk-NDI ( Bronze )
Defeat 30 enemies with the Mk-NDI.
30 Kills: Moss - 12 ( Bronze )
Defeat 30 enemies with the Moss - 12.
30 Kills: RPG - 7 ( Bronze )
Defeat 30 enemies with the RPG - 7.
30 Kills: Wes - 44 ( Bronze )
Defeat 30 enemies with the Wes - 44.
50 Kills: 92FS - 9mm ( Bronze )
Defeat 50 enemies with the 92FS - 9mm.
50 Kills: Dragon Sniper ( Bronze )
Defeat 50 enemies with the Dragon Sniper.
50 Kills: M32 - Hammer ( Bronze )
Defeat 50 enemies with the M32.
50 Kills: Micro - 9mm ( Bronze )
Defeat 50 enemies with the Micro - 9mm.
70 Kills: FAL ( Bronze )
Defeat 70 enemies with the FAL.
70 Kills: M4 ( Bronze )
Defeat 70 enemies with the M4.
70 Kills: SAS - 12 ( Bronze )
Defeat 70 enemies with the SAS - 12.
Apprentice Fortune Hunter ( Bronze )
Find ten treasures.
Bare-knuckle Brawler ( Bronze )
Defeat 20 enemies with hand-to-hand combat.
Bare-knuckle Expert ( Silver )
Defeat ten enemies in a row with hand-to-hand combat.
Bare-knuckle Slugger ( Silver )
Defeat 50 enemies with hand-to-hand combat.
Buddy System ( Bronze )
Complete one Cooperative Multiplayer game.
Cadet Fortune Hunter ( Bronze )
Find 30 treasures.
Charted - Crushing ( Gold )
Finish the game in Crushing Mode.
Charted - Easy ( Silver )
Finish the game in Easy Mode.
Charted - Hard ( Gold )
Finish the game in Hard Mode.
Charted - Normal ( Gold )
Finish the game in Normal Mode.
Crack Fortune Hunter ( Bronze )
Find 90 treasures.
Expert Fortune Hunter ( Bronze )
Find 80 treasures.
First Treasure ( Bronze )
Find one treasure.
Grenade Hangman ( Bronze )
Defeat ten enemies with grenades by aiming while hanging.
Hangman ( Bronze )
Defeat 20 enemies with gunfire by aiming while hanging.
Headshot Expert ( Bronze )
Defeat five enemies in a row with headshots.
Intermediate Fortune Hunter ( Bronze )
Find 40 treasures.
Master Fortune Hunter ( Silver )
Find all 100 treasures.
Master Ninja ( Silver )
Defeat 50 enemies with stealth attacks.
Novice Fortune Hunter ( Bronze )
Find 20 Treasures.
Platinum ( Platinum )
Platinum.
Practiced Fortune Hunter ( Bronze )
Find 50 treasures.
Professional Fortune Hunter ( Bronze )
Find 70 treasures.
Proficient Fortune Hunter ( Bronze )
Find 60 treasures.
Relic Finder ( Bronze )
Find the Strange Relic.
Run-and-Gunner ( Bronze )
Defeat 20 enemies by shooting from the hip ( without aiming with L1).
Steel Fist Expert ( Silver )
Defeat ten enemies in a row with a single punch, after softening them up with gunfire.
Steel Fist Master ( Bronze )
Defeat 20 enemies with a single punch, after softening them up with gunfire.
Survivor ( Silver )
Defeat 75 enemies in a row without dying.
Thrillseeker ( Bronze )
Complete one Competitive Multiplayer game.
Triple Dyno-Might ( Bronze )
Defeat three enemies with one explosion.
Tweaks on a difficulty you haven't finished
1. Start a game on a difficulty you haven't finished and go all the way until you have a real gun.
2. Go to in-game option and set the difficulty to one that you have the tweaks unlocked with.
3. Enable your tweaks.
4. "Save and quit".
5. Go to main menu option and set the difficulty back to the one you originally choose.
6. "Continue" the game.
7. Enjoy.
Uncharted 1 signage
On the "Urban Warfare" chapter and "Their Coming With Us" chapters, the climb-able signs hold references to Uncharted 1. For instance: Club Raja (Which references Eddy Raja from the first game) and Hotel El Dorado (which references the MacGuffin of the first game).
Uncharted: Drakes Fortune reference
When you are prompted to view your journal by pressing Select, you will find a picture labeled "Angry Eddy". Eddy was one of Drake's enemies from Uncharted: Drakes Fortune.
One of the unlockable guns for single player mode, is a gun used by Angry Eddy.
Unlimited money
Complete a task that rewards you with a large amount of money. Save the game if it is not at an auto-save area. Exit out to the main menu. Load the game again and you will get the reward once more. Repeat this as many times as desired.