At the start of Mission 2: Edge Of The World, proceed through the Bloodfly infested building to the upper floor. You will find an infected enemy and the key to the Black Market shop. Collect the key and return to the Black Market at the start of the mission. Climb through the window behind the shop and open the door with the key to get the "Black Market Burglar" trophy.
Easy "Circle Of Life" trophy
To do this, you must play as Corvo and buy all of his possession skills by the time you reach Mission 5: The Royal Conservatory (costs 13 runes). If you spend too many runes on other skills or do not find enough runes, you cannot do this. In the area with the Watch Tower (after the first Wall Of Light), make sure you are not spotted and do not kill anyone. Go to the place shown in the video and possess the hound, rats, bloodfly, human, and fish (in that order). You have very limited time to do this. After a few seconds the possession ends -- so you must be quick. Create a manual save backup before entering the area with the Watch Tower so you can retry if you make any mistakes.
Easy "Clockwork Collector" trophy
While inside the mansion in Mission 4: The Clockwork Mansion (where you have to find and eliminate Jindosh), you will encounter robots that will attack when causing trouble or making a lot of noise. You must destroy three of those Clockwork Robots and then pick up their plaque from the floor after they self-destruct to get the "Clockwork Collector" trophy. Start by taking their head off (either with a ranged weapon or hold [Melee] for a range strike). It should only take 2-3 hits to take their head off. Then, run around them in circles and hit all body parts with your sword until the yellow armor falls off. They will blow themselves up after taking too much damage and leave a plaque.
Easy "Counter-serum" trophy
During Mission 3: The Good Doctor, one of your main objectives will be to talk to Dr. Hypatia. To get the "Counter-serum" trophy, you must cure her by crafting the anti-serum. Do not kill her or you will not be able to get the trophy. When you talk to her in the morgue, check for a dying patient in the back of the room. He will give you a side quest and the combination to a safe. Grab the counter-serum formula from the safe and craft it. Then, inject it into Dr. Hypatia by performing a non-lethal takedown on her (R1). Complete the mission and you will be aboard the Dreadful Wale (your ship/hub area). Talk to Dr. Hypatia on the ship to get the trophy.
Easy "Dilapidation" trophy
This can be done immediately after getting the Timepiece item in Mission 7: A Crack In The Slab. Leave the room where you obtained the Timepiece, and switch to the past. In the long corridor, go through the first door on the right, jump up the shelf in the kitchen, switch to present time, and go through the opening in the wall. You will now be in a new area with a balcony. Switch to past time and shoot the two support beams off the balcony. When you switch back to present time, the balcony will have collapsed. Climb up to get the "Dilapidation" trophy.
Easy "Fatal Redirect" trophy
To kill an enemy with their own bullet, you need the "Reflexes" and "Superior Deflection" skills, which costs a total of three runes. Both Emily and Corvo have these skills. With these skills, all projectiles shot at you will will now be deflected to the nearest enemy while blocking. Hold Block and look for an enemy with a pistol. They wear red clothing -- the first few can be found in Mission 2. You can first damage them with your sword if desired. Only the final hit has to be their own bullet. Eliminate all other enemies in the area so the bullets are not redirected at them.
Easy "Fearless Fall" trophy
When Mission 3: The Good Doctor begins, go straight to the rooftop of the hospital. You can either use the elevator or your traversal powers to get up there. Stand on the arch (edge of rooftop) and jump down onto an enemy. You must kill the enemy by pressing [Melee] just before hitting the ground to get the "Fearless Fall" trophy. You can lure enemies to specific locations by shooting the crossbow or throwing an explosive (the crossbow is best for this). The enemies will investigate the impact point of your crossbow bolt. This makes it much easier to get them in a good position for you to jump on.
Easy "Flooded Basement" trophy
This can be done immediately after getting the Timepiece item in Mission 7: A Crack In The Slab. Leave the room where you obtained the Timepiece, and switch to the past. In the long corridor, go through the first door on the right, jump up the shelf in the kitchen, switch to present time, and go through the opening in the wall. You will now be in a new area. Go around the left side and down to the basement. Switch to past time. There will be two soldiers in the basement. Near them is a crank-wheel and a hole in the wall. Throw the crank through the hole. Switch to present time and place the wheel on the underwater pipe. You can then drain the water to reveal the hidden rune and get the "Flooded Basement" trophy.
Easy "Freedom Of Speech" trophy
While on the streets of Dunwall (after escaping the palace) in Mission 1: A Long Day In Dunwall, you will pass by a place called "Dunwall Courier". It is a building on the left of the road before going to the harbor. Go to the top floor to see the Printer being threatened by a soldier. Stab the soldier, then talk to the Printer afterwards (he will run into a side room) to get the "Freedom Of Speech" trophy after the dialogue.
Easy "Gazebo" trophy
Early in Mission 9: Death To The Empress, you will have to enter the courtyard of Dunwall Tower. There are many witches gathered around the courtyard/garden area. In the gazebo in the garden is a memorial for Jessamine. Interact with it to get the "Gazebo" trophy.
Easy "Heartbeat Reaper" trophy
Shortly after getting past the Wall Of Light in Mission 2: Edge Of The World, you will reach Addermire Station -- a large train station with several enemies and another Wall Of Light inside. This is just before entering the carriage. If you enter the carriage, you have gone too far and it will end the mission. Behind the registration is an armory, where you can find several grenades. Collect the grenades and alert all the enemies around the building. Lure them to the armory, then throw one of the grenades when they are standing close together in the room. The grenades have a large blast radius and will instantly kill all enemies. You can easily get 10+ kills in this area if you lure enough enemies.
Easy "Morbid Theft" trophy
When Mission 2: Edge Of The World begins, go straight to the Black Market shop and climb out the window on the back to find a woman named Mindy Blanchard. Talk to her and complete her side quest to get the "Morbid Theft" trophy. She will ask you to get a certain dead body from the Overseer Outpost and bring it to her.
Easy "Oracular Echoes" trophy
After getting past the first Wall Of Light in Mission 5: The Royal Conservatory, you will reach an area with a watchtower and another Wall Of Light. Proceed through that area to reach a large building with a lot of Witches (same building where you have to defeat the main target). In the main hall, go up the first flight of stairs to find a shrine on the balcony with blue glowing markings on the ground. It also has drawings of blue aliens and a machine with a switch. Activate the switch to trigger the voices. Activate it three times to listen to all the voices and get the "Oracular Echoes" trophy. Make sure to wait there until they are done talking.
Easy Jindosh Lock combination solution
In Mission 6: The Dust District, you will encounter the Jindosh Lock. The Jindosh Lock combination is randomized and different for every player and changes with each playthrough. However, you can easily solve it every time by creating a manual save game at the start of the mission, when talking to Meagan Foster (before killing either of the gang bosses). Then, kill and deliver one of the gang bosses to the other. They will give you the combination for your Jindosh Lock. Write down the combination. Then, reload the manual saved game you previously created. Go to the Jindosh Lock and enter the code you wrote down to unlock it and get the "Eureka" trophy. This is also very useful during a stealth run. Use the same method, then reload the manual save and enter the code to skip the entire mission. After opening the Jindosh Lock, the mission will immediately end.
Electroshock Machine puzzle solution
The Electroshock Machine puzzle is at the end of Mission 4: The Clockwork Mansion, when you finally meet with Kirin Jindosh. You can choose from two options. You can kill Kirin or place him in the Electroshock Machine. If you choose the Electroshock Machine, you have to create enough power to flip the switch next to the electric chair Kirin is sitting in. There are two nearby terminals that you can use that list various options such as Weaponry, Anatomy, Optics, etc. There is 11 power available and the Electroshock Machine requires 7 -- so you need to make sure the other two panels do not exceed 4. To simply do this, select Anatomy and Optics to have enough power.
Outsider Shrines
There are 5 Outsider Shrines in the game. Visit each one to obtain runes and information pertaining to the character after whom the shrines are named.
High Overseer Campbell - Look for Granny Rags, who is located in her apartment near the balcony. Through her back door, you'll find an alley with a shrine.
The Royal Physician - You should see a strange building, not far from Lord Pratchett's house. To access it, use your Blink spell while positioned on Pratchett's roof. Inside the building, you'll find a shrine.
Lady Boyle's Last Party - Not far from Boyle's Estate, you will find a (mostly) abandoned building that now is populated by Weeper foes. Ascend to the building's upper levels to find the shrine.
Return To The Tower - In the torture chamber, look for floors that descend to the building's first floor. Head down those stairs to reach the shrine.
The Flooded District - If you have completed sub-missions for Granny Rags and Slackjaw, you can find the characters in the district sewers. Talk to them and then head through the door near the furnace to find the final shrine.
Safe Combinations
At various points in the campaign, you will come across safes. Some missions have more than one safe, and safes may open to more than one combination. Below, you will find known combinations for the corresponding safe.
To find all of the Sokolov paintings, look in the areas described below. Some areas contain more than one painting. If you're having trouble, you can use the Heart to make the search a bit easier.
High Overseer Campbell - Gain entry to the mansion's basement, which you can enter by pressing a hidden button that is located on the wall just across from the kennel's entrance. Once inside the basement, explore to find the painting.
House Of Pleasure - At the Golden Cat, question the art dealer to learn the combination for his safe. You can find three paintings in the apartment: one in the safe, one in a guarded room on the second floor, and one in the bedroom located on the third floor.
The Royal Physician - Tend to the guards on the first floor in Sokolov's house, then take the painting they were protecting.
Lady Boyle's Last Party - At the point when you are looking for a Boyle sister, do a bit of looking around. Near where you find the target of your search, you will also find a painting. A second painting, meanwhile, is located on the mansion's second floor. Look for it near center of the show room.
Return To The Tower - Look for a room with a conspicuous fireplace, on the second floor inside the tower. The painting is hanging above that fireplace, in plain sight.
The Flooded District - A ruined building with three floors is located in the Waterfront region. Ascend to the third floor and use the Blink spell to snag the painting before you head for the refinery. After you clear out the Assassins' Headquarters building, look for a chain as you are leaving.
You can climb along it to find a platform on your descent. There you will find a second painting. Then seek out a third painting in the sewers, near the Old Port District Outskirts. It is upstairs from the area where you deal with Granny Rags.
Stilton's Master Key location
Shortly after Mission 7: A Crack In The Slab begins, you will receive the "Timepiece" item that allows you to time travel. Immediately after getting the Timepiece, go to the far end of the corridor. Switch between past and present time to get through it undetected. Press Square to see where enemies are in the other timeline. Stilton's Master Key is in the room at the end of the corridor. Switch to present time when you enter the room, crawl under the table, switch to past time, and collect the key to get the "Under The Table" trophy.
Thief: The Dark Project Reference
Proceed through Mission 7: The Flooded District, until you arrive at the Assassin's Hideout location in Central Rudshore. Your overall objective at that building is to meet with the primary target, but your approach matters. Sneak inside to avoid alerting your enemies. Once inside, look for a training area. Two assassins are positioned near one another, and one of them congratulates the other on a job well done. "I did not see you approach," he comments, which is the same dialogue you might recall hearing if you completed the stealth training tutorial in Thief: The Dark Project.
Various Trophies
Complete the following tasks to unlock PlayStation 4 trophy rewards.
Trophy
How to unlock
Type
A Night In 1849 (secret)
Visited the past
Bronze
Acrobat
Eliminate 10 enemies with Drop Assassinations
Bronze
Alternative Approach
Finish an entire mission with no casualties
Bronze
Art Collector
Acquire all collectible paintings
Silver
Black Market Burglar
Rob a black market shop
Bronze
Circle Of Life
Cast possession, chaining between Human, Hound, Rat, Fish, and Bloodfly
Bronze
Clean Hands
Complete the game without killing anyone
Gold
Clockwork Collector
Obtain numbered plates for 3 Clockwork Soldiers
Silver
Counter-Serum
Chat with Dr. Hypatia aboard the Dreadful Wale
Bronze
Dilapidation
Find the hidden balcony passageway
Bronze
Down With the Duke (secret)
Eliminated Duke Luca Abele
Bronze
DUNWALL DAYS AND KARNACA NIGHTS
Earn all other Trophies for Dishonored 2
Platinum
Empire in Chaos
Complete the game in High Chaos
Silver
Eureka
Crack the Jindosh Lock without finding the solution elsewhere
Bronze
Faithful to the Abbey
Side with the Overseers in the Dust District
Bronze
Familiarity Breeds Contempt
Rob Galvani multiple times
Bronze
Fatal Redirect
Kill an enemy with their own bullet
Bronze
Fearless Fall
Drop from Addermire's highest point and take out an enemy below
Bronze
Flesh and Steal
Complete the game without supernatural powers
Silver
Flooded Basement
Drain the water to recover a Rune
Bronze
Freedom of Speech
Save the Printer of the Dunwall Courier
Bronze
Gazebo
Pay tribute to Jessamine one last time
Bronze
Ghostly
Finish an entire mission without being spotted
Bronze
Heart Whispers
Using the Heart, listen to the secrets of 40 different people
Bronze
Heartbeat Reaper
Eliminated 6 enemies in less than 1.5 seconds
Bronze
Howlers 'til the End
Side with the Howlers in the Dust District
Bronze
Imperial Seal (secret)
Recover your Signet Ring
Bronze
In Good Conscience
Complete the game in low chaos
Silver
Jewel of the South (secret)
Reached Karnaca
Bronze
Labyrinthine Mind (secret)
Found Anton Sokolov in the Clockwork Mansion
Bronze
Morbid Theft
Steal a corpse for Mindy Blanchard
Bronze
Occult Carver
Craft 10 Bonecharms
Bronze
Oracular Echoes
Listen to the voices of the Sisters of the Oracular Order
Bronze
Place of Three Deaths
Kill Paolo three times
Bronze
Rogue
Eliminate 20 unaware enemies
Bronze
Royal Spymaster
Peruse all journals and audiographs by Meagan Foster and Anton Sokolov aboard the Dreadful Wale
Bronze
Shadow
Finish the game without being spotted
Gold
Silence
Eliminate Jindosh without him ever knowing you were there
Bronze
Sliding Marksman
Score a headshot while sliding
Bronze
Songs of Serkonos
Find 3 musical duos across Karnaca, and listen to their songs
Bronze
Souvenirs
Collect all the decorative objects for the Dreadful Wale
Silver
Spirit Thief (secret)
Took Delilah's Soul
Bronze
Stay of Execution
Stop the Grand Guard from pushing someone into the Wall of Light
Bronze
The Beast Within (secret)
Dealt with Dr. Alexandria Hypatia
Bronze
The Empress
Finish the game with Emily Kaldwin
Silver
The Greatest Gift (secret)
Saved your last known family member
Bronze
The Lovers
Link 2 characters with Domino just before one kills the other
Bronze
The Royal Protector
Finish the game with Corvo Attano
Silver
Under the Table
Obtain Stilton's Master Key from under the table, with the guards there conscious & unalerted