Win the gold medal in each challenge map to unlock Infinite Mode, where you fight endless waves of enemies with no time limit. While in Infinite Mode Deadpool will appear in an alternate costume, but the costume can only be used in that stage's Infinite Mode.

Unlockable	How to unlock
Ballerina Deadpool	Gold Medal in Great White News HQ.
Chef Deadpool	Gold Medal in Citadel Courtyard.
Classic Deadpool	Gold Medal in The Watching Sentinel.
Classic X-Men Uniform	Gold Medal In Beneath the Streets.
French Maid Deadpool	Gold Medal In Magneto's Prison.
Ultimate Deadpool	Gold Medal in Catacombs of Genosha.
X-Men Costume	Gold Medal in Office Spaces.