When you get the key to enter the spider room as Claire, move the crate blocking the door so you will not have to fight the Ironhead when you return to this area. You will be able to run directly through. At the end of Claire's segment, crouch under the spinning blade in the corner. Note: This also works for Invisible mode. Lure the first wave into the traps. Claire can now easily hold off the two at a time spawns while Moira opens the hatch. This allows you to easily complete the last section when low on ammunition and make things easier for Barry. If you did not use the flame bust during Claire's campaign, you can walk out the door with Barry without activating the control room console.