Start with the Simian Flu under the casual difficulty setting. Genes will not matter. The ATP boost might speed things up, but is not necessary. Choose either the USA or Saudi Arabia. Progress as usual, popping DNA bubbles, until you have enough to evolve the "Simian Neuro-Genesis", which should cost 15 DNA points at the "Abilities" screen. Afterwards you will get the option to Devolve it at the cost of more DNA points.
Easy "Do it like they do" achievement
With the Simian Flu, evolve Primal Hunt and Social Cohesion.
Easy "Is it a bird?" achievement
Using Necroa Virus, combine the Vampiric Hunger symptom (Cytopathic Reanimation + Anaerobic Resuscitation + Enhanced Sensory Integration + Temporal Lobe Manipulation + Cathemeral Shift) and the Bat 1 + Bat 2 transmissions.
Easy "Jaws" achievement
Play the Necroa Virus scenario and evolve your virus to have both the Hyperosmia and Delirium traits under the "Symptoms" tab.
Easy "Like flies round" achievement
With the Simian Flu disease, evolve Diarrhea and Hominidae Bridge.
Easy "Long Shot" achievement
Evolve the Coughing and Vomiting symptoms.
Easy "Normal Shuffle" Achievement
Like some other achievements, you can save right before you win, reload the save 4 time, and get the achievement.
Easy "Oink oink" achievement
Evolve the Coughing, Diarrhea, Nausea, Pneumonia and Vomiting symptoms; as well as evolving the Livestock 1 + Livestock 2 transmissions.
Easy "Patient Who?" achievement
Start a normal non-scenario game of Prion under the casual difficulty setting. Prion can slow down the cure forcing a longer game. Start in Saudi Arabia. Then, evolve the following in order as soon as possible: Air 1 and 2, Water 1, Neural Atrophy 1, 2, and 3, Drug Resistance, and Genetic Hardening 1 and 2. Note: Devolve every mutated symptom as soon as it appears. Evolve the following symptoms: Coughing, Sneezing, Pneumonia, Cysts, Hyper Sensitivity, Abscesses, Insomnia, and Paranoia. You will have to wait at this point, devolving all mutated symptoms. Even if the symptom is non-lethal it must still be devolved. Immediately pop the cure bubbles as they appear. If the cure progress reaches 75%, immediately evolve all three Genetic Re-Shuffles. You will eventually see the message "CDC teams hunt patient zero" followed after a few months by "CDC teams close on patient zero". Evolve the following symptoms immediately: Anaemia, Haemophilia, Internal Haemorrhaging, and Hemorrhagic Shock. They should begin killing the population at a decent rate. Do not have any more lethal symptoms, as you will need time for the final pop-up to appear. After nearly half the world us killed, the message "CDC fails to identify patient zero" should appear.
Easy "Peer Pressure" achievement
Have no symptoms and your starting country at 100% infection. You must remain at no symptoms until "Peer Pressure" is earned. Consider using Bacteria and start in a small poor country, such as Zimbabwe or Kazakhstan.
Easy "Published Scenario" achievement
Upload a scenario then earn any other achievement.
Easy "Red Ape Redemption" achievement
Unlock Horse Riding and Weapon Creation. This may require some time.
Easy "Red Rain" achievement
Evolve the Haemophilia and Skin Lesions symptoms.
Easy "Rude Awakening" achievement
With the Simian Flu, evolve Scouts and Excrement.
Easy "Runner" achievement
Using Necroa Virus, combine the Enhanced Motor Control symptom and the Engorged Quadriceps ability.
Easy "Shouldn't Keep Pets" achievement
Make all apes intelligent and move them into a single colony. Move the colony across an ocean.
Easy "Spitter" achievement
Using Necroa Virus, combine the Naja Mortis and Enhanced Sensory Integration symptoms.
Easy "STALKERs delight" achievement
Some luck is required to earn this achievement. If you get popup stating "New round of nuclear tests considered", evolve the Insanity symptom to increase the chance of it happening.
Easy "Tank" achievement
Using Necroa Virus, evolve the Bone Dysplasia and Anabolic Boost symptoms.
Easy "Tasty" achievement
Using Necroa Virus.,eEvolve the Polyphagia, Autophagia and Cannibalism symptoms.
Easy "Touchscreen Trash" achievement
After the iCure is launched, unlock the "Sweating" symptom. Note: "Sweating" is in the second option from the top right of the standard symptom tree.
Easy "Uh Oh" achievement
Evolve the Diarrhea and Sneezing symptoms.
Easy "Use your head" achievement
Using Necroa Virus, combine the Cranial Elephantitis symptom and Air 3 transmission.
Easy "Walking Contradiction" achievement
Using Necroa Virus, combine the Photophobia and Cathameral Shift symptoms.
Easy "Who needs DEET" achievement
Note: This may require some time as it is luck based. When you get a popup stating that there has been an insect population boom, which increases zombie decay rates, immediately evolve the Zoonotic Shift and Insect transmissions. Zombies will now repel insects, returning their decay rate to normal.
Let'sEvolved
Name your virus "Let'sEvolved" and you gain 100 points at the beginning.
Various Achievements
Complete the following achievements to unlock Microsoft Gamerscore points.
Achievement
How to unlock
Assuming Direct Control (5 points)
Win a game by enslaving humanity with the Neurax Worm.
Bacteria Master (15 points)
Beat Bacteria on mega-brutal difficulty.
Bacteria Victory (10 points)
Win a game with Bacteria on Normal Difficulty or higher.
Banana Skin (10 points)
Prevent PfiGlax modifing the Necroa Virus.
Big Bang (10 points)
Kill the DarkWater research team.
Bingo! (10 points)
Win 5 times in a row on normal difficulty with the lucky dip strain enabled.
Bio-Weapon Victory (10 points)
Win a game with Bio-Weapon on Normal Difficulty or higher.
Bioweapon Master (15 points)
Beat Bioweapon disease type on mega-brutal difficulty.
Boomer (5 points)
Discover the Boomer combo.
Bottle Smasher (5 points)
Smash a Blue cure bubble and slow down the Research Team.
Brainzzzz (5 points)
Discover the Waking Dead combo.
Breathe Deep (10 points)
Infect the Chernobyl research team.
Brown Streets (5 points)
Discover the Public Defecation combo.
Call PETA (5 points)
Make a celebrity cry.
Chinese Nuclear Retaliation (25 points)
Make the USA nuke China.
Complete Artificial Organs (10 points)
Score 3 biohazards with Artificial Organs scenario.
Complete Black Death (10 points)
Score 3 biohazards with Black Death scenario.
Complete Created Equal (10 points)
Score 3 biohazards with Created Equal scenario.
Complete Frozen Virus (10 points)
Score 3 biohazards with Frozen Virus scenario.
Complete Global Warming (10 points)
Score 3 biohazards with Global Warming scenario.
Complete Golden Age (10 points)
Score 3 biohazards with Golden Age scenario.
Complete Ice Age (10 points)
Score 3 biohazards with Ice Age scenario.
Complete Mirror Earth (10 points)
Score 3 biohazards with Mirror Earth scenario.
Complete Nipah Virus (10 points)
Score 3 biohazards with Nipah Virus scenario.
Complete Pirate Plague (20 points)
Score 3 biohazards in the Pirate Plague scenario.
Complete Santa's Little Helper (10 points)
Score 3 biohazards in the Santa's Little Helper scenario.
Complete Shut Down Everything (20 points)
Score 3 biohazards in the Shut Down Everything scenario.
Complete Smallpox (10 points)
Score 3 biohazards with Smallpox scenario.
Complete Sovereign Default (10 points)
Score 3 biohazards with Sovereign Default scenario.
Complete Swine Flu (10 points)
Score 3 biohazards with Swine Flu scenario.
Complete Teleportation (10 points)
Score 3 biohazards in the Teleportation scenario.
Complete Unknown Origin (10 points)
Score 3 biohazards with Unknown Origin scenario.
Complete Volcanic Ash (20 points)
Score 3 biohazards in the Volcanic Ash scenario.
Complete Who Cares (10 points)
Score 3 biohazards with Who Cares scenario.
Complete Xenophobia (10 points)
Score 3 biohazards with Xenophobia scenario.
Contagion Cancelled (5 points)
Prevent a film about your plague being made.
Contaminated Package (5 points)
Let humans spread the disease via blood transfusion.
Dead End (10 points)
Stop DarkWater from discovering a Necroa Virus weakness.
Don't Ask Me (10 points)
Make the PfiGlax modification project fail.
Due Diligence (10 points)
Stop PfiGlax finding a link to the Necroa Virus.
Evolve your disease (5 points)
Evolve your disease to become stronger.
Flash Mob (5 points)
Successfully use the Zombie Horde active ability.
Fungus Master (15 points)
Beat Fungus disease type on mega-brutal difficulty.
Fungus Victory (10 points)
Win a game with Fungus on Normal Difficulty or higher.
GLaDOS Says Hi (5 points)
Make a teleport attempt end in tragedy.
Getting Colder (10 points)
Trick the Egyptian DNA tests.
Hide and Seek (10 points)
Prevent link with Chernobyl exclusion zone.
I never asked for this (5 points)
Feel the negative side of artificial organs.
I'll Be Back (5 points)
Successfully use the Zombie re-animate active ability.
Insane Bolt (10 points)
Sprint to victory and set a world record by winning the game with Bacteria in under 365 days.
Is it a bird? (5 points)
Discover the Vampire Bat combo.
It's a Trap! (10 points)
Wipe out the Giza expedition.
Jaws (5 points)
Discover the Blood in the Air combo.
Lava God (20 points)
Get 3 biohazards with each disease on normal or higher in the Volcanic Ash Scenario.
Long Shot (5 points)
Discover the Projectile Vomiting combo.
Mr President (20 points)
Get 3 biohazards with each disease on normal or higher in the Shut Down Everything Scenario.
Nano-Virus Master (15 points)
Beat Nano-Virus disease type on mega-brutal difficulty.
Nano-Virus Victory (10 points)
Win a game with Nano-Virus on Normal Difficulty or higher.
Necroa Master (15 points)
Beat Necroa Virus disease type on mega-brutal difficulty.
Neurax Master (15 points)
Beat Neurax Worm disease type on mega-brutal difficulty.
Neurax Worm Victory (10 points)
Win a game with Neurax Worm on Normal Difficulty or higher.
Non Starter (10 points)
Stop DarkWater from analysing the Necroa Virus.
Normal Shuffle (10 points)
Win 5 times in a row on normal difficulty with the shuffle strain enabled.
Not Another Zombie Game (25 points)
Win a game with the Necroa Virus without making a single zombie.
Oink oink (5 points)
Discover the Swineflu Combo.
Olympic Spoiler (10 points)
Help the Olympics go viral in the UK.
On The Naughty List (5 points)
Put humanity on Santa's naughty list.
Parasite Master (15 points)
Beat Parasite disease type on mega-brutal difficulty.
Parasite Victory (10 points)
Win a game with Parasite on Normal Difficulty or higher.
Patient Who? (5 points)
Stop the CDC finding Patient Zero.
Peer Pressure (10 points)
Have your plague discovered after riots force a government investigation.
Plague in Space (25 points)
Infect astronauts before they launch a space mission.
Prion Master (15 points)
Beat Prion disease type on mega-brutal difficulty.
Prion Victory (10 points)
Win a game with Prion on Normal Difficulty or higher.
RMS Watch List (5 points)
Get your Plague on the RMS Watch List.
Red Rain (5 points)
Discover the Profuse Bleeding combo.
Revenge of Osiris (10 points)
Invalidate the knowledge of the pharaohs.
Runner (5 points)
Discover the Runner combo.
Russian Nuclear Retaliation (25 points)
Make the USA nuke Russia.
STALKERs delight (10 points)
Cause a nuclear meltdown.
Spitter (5 points)
Discover the Spitter combo.
Super Sparrow (20 points)
Get 3 biohazards with each disease on normal or higher in the Pirate Plague Scenario.
Tank (5 points)
Discover the Tank combo.
Tasty (5 points)
Discover the Bath Time combo.
Test This! (10 points)
Force Chernobyl research to be put on hold.
The End Plague (10 points)
Win one game with any disease type and any difficulty.
The Glorious Dead (10 points)
Win a game with the Necroa Virus.
Touchscreen Trash (5 points)
Disrupt the iCure and stop it helping cure research.
Trojan Horse (5 points)
Create a trojan plane and use it to infect a new country with the Neurax Worm.
Uh Oh (5 points)
Discover the Oops symptom combo.
Ultimate Christmas (5 points)
Discover the Ultimate Christmas Combo.
Unlock Cheatmodes (10 points)
Unlock the cheats by winning a game on Normal for ALL disease types.
Use your head (5 points)
Discover the Cranial Dispersion combo.
Virus Master (15 points)
Beat Virus disease type on mega-brutal difficulty.
Virus Victory (10 points)
Win a game with Virus on Normal Difficulty or higher.
Walking Contradiction (5 points)
Discover the Walking Contradiction combo.
Who needs DEET (5 points)
Avoid insect bites.
Who needs brains (10 points)
Take humanity back to the stone age.
Worm Food (10 points)
Win a game by eradicating humanity with the Neurax Worm.
