Successfully complete the game and allow it to auto-save after the credits. Load the cleared saved game file repeatedly until the game starts again with all your previously purchased moves and collectibles. Note: Do not skip through the credits when starting your reloaded saved games.
Costumes
To unlock the desired costume, perform the actions listed below:
Armor - Complete Act 2
Ben Reily - Complete 25 city events
Cosmic Spider-Man - Complete Act 1
Iron Man - Collect 150 Spider Tokens
Carnage - Defeat 500 enemies
Spider-Man 2099 - Complete 50 city events
Play Again
To unlock the option to play through the game with previous upgrades, beat the game once through. Keep in mind that you have to cycle through the end credits once, then hit Continue from the game's main menu before going through the credits a second time. Hereafter, you can begin a new game with all of your upgrades (and more) from your previous save.
Spidey Icon Locations
If you want to see where any Spidey Icon is that you've yet acquired, collect 1,000 Spidey Icons or get to level ten.
Use both superhero and villain strikes
Notice as Spider-Man uses both his red and blue/black suits, his alignment meter will progress toward his good or bad side respectively. Take a look at the photo in the lower left-hand corner of the screen as well as the alignment meter in the pause menu. While the alignment picture is displaying the red and blue suit, only superheroes will aid him, and conversely while the black symbiote is displayed, only villains will help. As long as the picture is one color, it does not matter what suit you use until the meter color crosses the middle. If you maintain a very close middle ground, you can effectively utilize both the superheroes and villains (although not at the same time.) Strategize by getting both red and black points until your alignment meter is precisely in the middle. You might notice as you defeat one enemy using a suit that Spidey's picture will change in the lower left hand corner of the screen. Even if you have a hero summoned, if you quickly switch to the black suit and defeat more of the enemies until the photo changes, that hero will still stay with you until you dismiss him or your special meter runs out. The same holds true for villains and switching back to the red suit. The alignment affects whom you can summon, not who you have already called in. Use this strategy to defeat your enemies, get the most experience points, and unlock all the moves.
Wolverine's quiz
When you first meet Wolverine, he will attack and you must fight him. He will ask a series of questions that must be answered correctly. Use the following responses to pass the quiz.
Richard and Mary
Ned Leeds
Battleworld
Daredevil
A Mutant
May Parker