Cheat Codes
Display the Seed entry prompt at the "Character Select" menu. Then, enter one of the following seed codes to activate the corresponding cheat function. Note: Some codes may delete your saved game file.
| Effect | Code
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- All enemies have permanently feared
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- All floors have the basement room tile set
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- All items except troll bombs mimic Issac's movement
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- Character and tears turn black
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- Character leaves fecal trail
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- Character only visible as brown shadow
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- Character takes double damage
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- Concussive enemies that move randomly
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- Doors open immediately, tears are harmless; Boss's health act as timers
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- Eligible enemies become champions
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- Enemies become feared randomly
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- Enemies only visible as brown shadows
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- Enemies respawn when character leaves room; new items do not drop
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- Invisible character except for surrounding light effect
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- Large pools of blood when enemies die
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- Load screen always displays "Are You Sure You Want Me To Die?"
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- Pill names and descriptions appear as ???
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- Slow motion while character is idle; music speed altered with movement speed
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- Sound effects replaced with farts
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- Start with 69 coins and have to purchase all items and pickups
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- Tarot cards are face down when collected
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- The lower your health, the slower the music
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- Ticking starts every 45 seconds, after 5 seconds character takes half heart of damage
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Easy items
This trick requires the Blank Card (from defeating Isaac in the Cathedral with Eden), Jera Rune (from completing the "High Brow" challenge), and the D20 (from defeating ??? in the Chest with Isaac). Having the D6 (from defeating Isaac in the Cathedral with ???) is also helpful. Start by finding a room that has at least one battery on the ground. Alternately, spawn them with the 48 Hour Energy pill. Remove all other items from the room. Use charges from somewhere else to copy those batteries with the Blank Card and Jera until you have at least three of them. Use batteries from the room to copy batteries for a net gain. Keep doing this until the room is filled with batteries to virtually have infinite charges for any activated item. Then, obtain a Judgement card (from Wheel Of Fortune cloning, Tarot Deck, etc.). Use the Blank Card and Jera in a new room to copy a large number of Judgement cards. Go to another new room, and copy a large number of coins, keys and hearts. Note: Try spawning a few Beggars and bombing them. Use the resources in this room to refill when required. If you need a D20, use the Judgement cards to spawn Beggars and farm them until you get one from a Key Beggar chest. Finally, use the following four steps to complete the process:
1. Fill the largest room available with items such as coins. A room is considered full when it starts replacing old items with new ones.
2. Use the D20 to reroll the items, open all the chests, pick up any passive items, pills, and other helpful objects and repeat. Avoid collecting items that are not needed.
3. Once a D6 drops, repeat the steps in a smaller room to get a few activated items. Swap any activated items that you want to keep elsewhere.
4. Reroll the items in the main room with the D6, collect anything desired, and repeat the process. Use the D20 to refill as needed.
New Items
By fulfilling certain conditions, you'll receive a notification that a new item (or items) have been unlocked. Any items unlocked this way have a chance of randomly appearing during subsequent runs, such as in shops or as rewards for beating bosses.
| Item | How to unlock
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| - Defeat Mom's Heart for the eighth time.
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| - Defeat Mom for the first time.
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| - Donate 150 Coins to the Donations Box.
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| - Donate 10 Coins to the Donations Box.
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| - Defeat a Harbinger for the first time.
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| - Defeat Mom for the first time.
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| - Defeat Mom's Heart for the ninth time.
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| - Defeat Mom's Heart for the seventh time.
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| - Defeat Krampus for the first time.
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| - Defeat Mom's Heart for the sixth time.
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| - Defeat C.H.A.D. for the first time.
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| - Complete The Caves (or equivalent level) for the first time.
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| - Defeat Gish for the first time.
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| - Complete The Basement (or equivalent level) for the first time.
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| - Donate 400 Coins to the Donations Box.
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| - Defeat Mom's Heart for the second time.
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| - Defeat each one of the Deadly Sin enemies.
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| - Defeat either Mom or Mom's Heart by activating The Bible.
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| - Donate 50 Coins to the Donations Box.
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| - Defeat Mom's Heart for the third time.
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| - Defeat Mom's Heart for the fourth time.
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Switch Exclusives
A lot of people have been asking about this things. They normally make theories and sometimes say the truth, but here I have discovered how to unlock these. It takes determination and skills (for real) 'cause this is HARD.
| Unlockable | How to unlock
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- Afterbirth + bosses and champion variants
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| - Defeat Mom's Heart 11 times.
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| - Donate 500 coins to the Greed Machine
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Azazel...