Use a text editor such as Notepad to edit the "defuser.ini" file in the game directory. Set a key binding to the following codes (for example, "F10=fly". Then, press the corresponding key during game play to activate the corresponding cheat function. Note: Any active codes are disabled when a new area loads or intermission sequence plays.
Effect - Code
God mode - god
Disable clipping - ghost
Flight mode - fly
Disable fly and ghost codes - walk
Teleport to pointer - teleport
Defeating Atlas Fontaine
This is the final Boss and he has three different styles of attacks:. Flame Plasmid Form, Ice Plasmid Form, and Electric Plasmid Form. The easiest way to defeat him in the first part is to use your Ice Plasmid and freeze him. Then, switch to your Telekinesis Plasmid. Grab an explosive tank and throw it at him. Also, if desired, just use your telekinesis. He is very predictable if you are far away from him. Wait for him to throw a fire ball at you then move out of the way. He will continue to run past you. Use this chance to fire the machine gun, which does the most damage to him. Once he goes back to his chamber to gain his life back, change to the Flame Plasmid and get ready for some bots. Once he starts his routine of fire and run, blast again him with the Flame Plasmid . The more you blast him, the faster he loses life. Continue to use the machine gun while he is aflame. He will now go back to his chamber one last time. He now has electrical powers. Keep your Flame Plasmid ready. This time, shoot him with the Flame Plasmid and he will run for the water. Once he jumps in the water and comes back out, hit him with it again. Be aware that there are splicers all over as well. Also set them ablaze to get some extra life. There are many different ways to defeat him but this seemed to be the easiest.
Defeating Peach Wilkins
When the dark cloud envelopes the icy battlefield upon which you must face Peach Wilkins, save the game and locate the hostile turret at the end of the room when the cloud clears. Load the game and run to it before the cloud clears, so that you can quickly freeze or shock it. Then, hack it so it shoots your enemies. Crouch down by the area to your right when facing the turret. There are a few barriers here to protect you from enemy fire. However, to avoid damage by Wilkins' grenades, keep Telekinesis as your active Plasmid. He will avoid the turret's fire, but as long as you stay behind the barriers by the turret he will stay at a safe distance. This gives you time to calmly return his grenades using Telekinesis until he dies. The turret will take out most of the Splicers. This method makes things much easier because it eliminates the hectic "run around and whack people with the wrench" strategy that is otherwise your only option. That turret if not used as an ally would probably be the main cause of your death, along with the bots triggered by the security camera. By hiding near the allied turret however, you also hide from the camera's view.
Defeating Rosies
When fighting a Rosie, use armor piercing rounds from the machine gun or pistol. For a more effective way of killing, launch frag grenades and run out a door. The Rosie will follow you, fire proximity mines at the door, and when it walks through it will be damaged or destroyed.
Defeating security robots
If you are up against a stationary security robot (RPG, etc.), use Telekenesis to grab a crate or pallet. Hold it in front of you until you can find a place to hide and plan what to do next. The item you hold up will block some attacks.
Defeating: Frank Fontaine
To defeat Frank Fontaine very fast, when you first enter the room hit him with the tool the Little Sisters gave you. Fight him when he throws you off. Once he is back on the bed, run up and hit him again with the tool to drain his Adam. This works a lot faster due to him only have four or five jars of Adam to drain, and the fights are not very long afterwards.
Easy kills
From the start you will have a wrench and the Electric Bolt Plasmid at your disposal. Using these is rapid succession against most Splicers can often result in an efficient, quick kill. First, shock the Splicer. Before the convulsion ends, switch out the wrench, aim high, and hit the Splicer over the head. The most efficient way of eliminating the agile Spider Splicers however is to unleash a few clips of anti-personnel ammo, preferably from the machine gun.
Easy Splicer Kills
Simply use Telekinesis on one to hurl a body at others. This method usually results in a one-hit kill and is especially useful against higher-level Splicers.
More Cheat Codes
First, find and open defuser.ini in the installation folder and set bind. Save file, start game, and press the bound key to toggle the key and enter the following codes...
givehealth - Gives Health
givebioammo - Gives EVE
igbigbucks - Gives $500
These cheats will turn off if you leave the area, or a cutscene appears.
Pac Man reference
In the Arcadia level, you will find a place that appears to be a bar. Search around a bit and you will see a block of cheese, followed by holes. The cheese is cut like Pac-Man himself. There are holes next to it, none of which can be gun shots. If you shoot the floor with any weapon you have, the marks will not match.
Post Patch Ver 1.1 cheats
Note: v1.1 of the game is required to enable all codes. Some, but not all, codes can be used with earlier versions. This procedure involves editing a game file; create a backup copy of the files before proceeding. You will need to allow hidden files and folders to be shown in order to edit this particular .ini file. Use a text editor to edit the "User.ini" file found in the following locations: Windows XP: C:\Documents and Settings\[username]\Application Data\Bioshock\ Windows Vista: C:\Users\[username]\AppData\Roaming\Bioshock\ Set a key binding in the User.ini file to any of the following codes (for example, "F10=fly"). Then, press the corresponding key during game play to activate the corresponding cheat function. Note: Any active codes are disabled when a new area loads or intermission sequence plays. General codes are as follows:
Code
Effect
setgravity [number]
Set gravity; "-1400,0" is default; "0.0" is no gravity
setjumpz [number]
Set jump height; "600.0" is default, more than "1200.0" will result in taking damage upon landing
Reaching Fontaine's penthouse
The code to get to Fontaine's penthouse is from the diary: "5744".
Restore hacked robot's health
After hacking a robot, it will begin firing at your enemies. If the robot gets hit it will begin to lose health, catch on fire, and eventually blow up. To stop this from happening, deactivate the robot, then reactivate it a few seconds later. This should make the robot have full health again.
Save game recommendation
After becoming a Big Daddy, make a new saved game. At this point you are near the end of the game. If you missed something you can go to the bathysphere and explore Rapture again, but also you are a Big Daddy now so the splicers will not harm you, security cameras will not set off alarms, etc.
Slot machine
Save the game before you start playing. Just keep reloading the game until you hit it.
Star Wars reference
Get to the point when you reach the medical pavilion and must unlock the doors. When you pull the first switch and go to the second, pull it and Atlas will say "Now you have stirred the Wookie cage".
Weapon Upgrade Station locations
1: In Peach Wilkins' hideout (Neptune's Bounty), bottom floor. As soon as you come downstairs it is directly in front of you.
2: On the way to Farmer's Market in Arcadia, the station is located to the left after you go up the first stairs coming from Tree Farm.
3: The Winery's basement in Farmer's Market. There is a flooded area with one of them attached to the wall. It is in front of you when you come down the stairs; just keep going forward.
4: In Fort Frolic, from the Atrium bottom floor, go towards the bathrooms. Then, move right and follow the path until you see some small stairs to your right leading up to a door. Go inside then go down into the basement. The basement is filled with cigars and the like. The upgrade station is on the wall.
5: Go to Poseidon Plaza in Fort Frolic. Go to the other end of the bottom floor (the opposite end of where you enter). Go into Sinclair Spirits (the room that has a corpse on a sort of "altar"). In the basement of this store is the station.
6: In Hephaestus Core Room, go down to the bottom floor and run around (literary). Eventually you will see it attached to the wall.
7: In Hephaestus, Kyburz's office. It is attached to the left wall (back turned to the entrance) in the rear of the room.
8: At the bottom floor of the Mercury Suites area, on the back of the center pillar.
9: In Sander Cohen's secret room, in the Olympus Heights' Mercury Suites area.
10: Go to Atlas' Headquarters in Apollo Square (Fontaine's Home For The Poor area). It is located on the fourth floor. Go down the stairs in the room and look to the right. The station will be in front of you.
11: When you enter Point Prometheus and chase Fontaine, eventually you will end up in a little square and Fontaine will go behind a locked Museum door. At the opposite end of this square (from where you came) is a dead Big Daddy. Next to it is the upgrade.
12: In the Voice changing labs in Point Prometheus, one of the labs has it.